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KMID : 0363220130510010049
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Korean Journal of Dermatology
2013 Volume.51 No. 1 p.49 ~ p.52
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Leukocytoclastic Vasulitis Induced by Methoxy Polyethylene Glycol-Epoetin Beta
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Lee Sang-Yoon
Go Jae-Wan
Kim Shin-Han
Son Hyun-Ok
Cho Han-Kyoung
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Abstract
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Methoxy polyethylene glycol-epoetin beta (Mircera(R), Roche), a third-generation erythropoiesis-stimulating agent (ESA) is known as a continuous erythropoietin receptor activator (CERA). In patients with anemia associated with chronic kidney disease (CKD), it is administered intravenously or subcutaneously. Treatment-related adverse events induced by methoxy polyethylene glycol-epoetin beta occurred in 6%. Hypertension, diarrhea and nasopharyngitis were the most commonly reported adverse events. Cutaneous adverse reactions are rarely experienced with methoxy polyethylene glycol-epoetin beta including maculopapular eruption, facial erythema, and tinea pedis. To the best of our knowledge, no cases of leukocytoclastic vasculitis associated with methoxy polyethylene glycol-epoetin beta have ever been published in medical literature. Herein, we report on a case of leukocytoclastic vasulitis induced by methoxy polyethylene glycol-epoetin beta in a patient with anemia associated with chronic kidney disease.
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KEYWORD
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Leukocytoclastic vasculitis, Methoxy polyethylene glycol-epoetin beta, Mircera(R)
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